N-glycosylation相关论文
＜正＞Background and Aims:Hepatitis B virus immune escape gives a challenge to prevention,diagnoses and treatment to hepatit......
目的:分析血清IgG N-糖链与胃癌Lauren分型的相关性。方法:对2017—2018年于复旦大学中山医院进行治疗的17例弥漫型和21例肠型胃癌......
Mass Spectrometry Analysis of Newly Emerging Coronavirus HCoV-19 Spike Protein and Human ACE2 Reveal
The coronavirus disease 2019(COVID-19)pandemic has led to worldwide efforts to understand the bio-logical traits of the ......
An E2 N-glycosylation mutant with enhancement of inducible cellular and neutralizing antibody respon
Introduction: Hepatitis C virus (HCV) vaccine candidates based on viral envelope glycoprotein E2 have shown notable effe......
Escherichia coli phytase appA belongs to the histidine acid phosphatase family.With a high hydrolytic activity towards p......
Many human major infectious disease pathogens have rich glycans(sugar chains and glycoconjugates)on the surfaces of micr......
Royal jelly (RJ) is a proteinaceous secretion from the hypopharyngeal and mandibular glands of nurse honeybee workers.It......
Characterization and high-yield production of non-N-glycosylated recombinant human BCMA-Fc in Pichia
B-cell maturation antigen(BCMA)fused at the C-terminus to the Fc portion of human IgG1(BCMA-Fc)blocks B-cellactivating f......
Two conserved oligosaccharyltransferase catalytic subunits STT3A and STT3B required for N-glycosylat
Asparagine(N)-linked glycosylation is one of the most crucial post-translational modifications,which is catalyzed in the......
Asparagine (Asn/N)-linked glycosylation is an important post-translational modification.Its multiple steps and consists ......
Background and Aims:Hepatitis B virus immune escape gives a challenge to prevention,diagnoses and treatment to hepalitis......
β-Mannanase has been widely used in industries such as food and feed processing and thus has been a target enzyme f......
β4GalT1 regulates the N-glycosylation of BMP2 and TNFR1 to promote microglial inflammatory activatio
Microglial inflammatory activation,as the center of neuroinflammation,greatly contributes to diverse neurodegenerati......
Glycosylation is a common posttranslational modifica-tion on membrane-associated and secreted proteins that is of pivota......
N-Glycosylation at Asn695 might suppress inducible nitric oxide synthase activity by disturbing elec
Inducible nitric oxide synthase(iNOS)plays critical roles in the inflammatory response and host defense.Previous researc......
人胰岛素为非糖基化修饰的蛋白质类激素,在生物体内的半衰期非常短.利用蛋白质经N-糖基化修饰后可以增强生物活性并延长其生物半衰......
,Biochemical features of the adhesion G protein-coupled receptor CD97 related to its auto-proteolysi
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,N-glycosylation at Asn residues 554 and 566 of E-cadherin affects cell cycle progression through ex
E-cadherin, which has a widely acknowledged role in mediating calcium-dependent cell-cell adhesion between epithelial ce......
,Generation of glyco-engineered BY2 cell lines with decreased expression of plant-specific glycoepit
Plants are known to be efficient hosts for the production of mammalian therapeutic proteins. However, plants produce com......
,N-Linked Glycosylation of the p24 Family Protein p24δ5 Modulates Retrograde Golgi-to-ER Transport o
The K/HDEL receptor ERD2 mediates the transport of soluble endoplasmic reticulum (ER)-resident proteins containing a C-t......
目的探索中国人群中免疫球蛋白G（IgG）糖基化与中心性肥胖的关联。方法采用横断面研究，整群抽样法于2012年4至7月在北京市西城区某社区......
目的：通过过表达N－糖基转移酶，构建1株糖基化修饰效率更高的糖基工程酵母。方法利用尿嘧啶（URA3）营养缺陷型筛选标记，在糖基工程酵母4－32......
N-糖基化对病毒的感染与增殖均具有重要作用,与PCV2复制相关的Rep蛋白含有三个N-糖基化位点.为了分析PCV2 Rep蛋白N-糖基化位点突......
Both HIV and EIAV belong to the retroviridae family and lentivirus genus. They share considerable similarity at gene str......
为探讨N-糖基化对植酸酶phy（ QF ）酶学性质的影响，将植酸酶基因phy（ QF ）在毕赤酵母中进行了表达，利用脱糖基化酶Endo Hf去除重组植酸酶p......
目的分析隐匿性HBV感染（OBI）患者HBV S基因主要亲水区（MHR）N-糖基化突变的抗原性,探讨N-糖基化突变与OBI发生机制的关系及临床意义。方......
目的 研究Ｎ－糖基化抑制交质瘤细胞生长状态的影响。方法 以仪霉素（ｔｕｎｉｃａｍｙｃｉｎ）为Ｎ－糖基化抑制对胶质瘤细胞生长的影响。结果 依素作用于ＳＷＯ－３８细胞后，透......
目的构建IL-24基因的真核表达载体,在毕赤酵母GS115中高效表达,研究重组N-糖基化IL-24蛋白体外诱导肿瘤细胞凋亡的活性。方法借助......
构建并表达人朊蛋白N-糖基化修饰位点突变的真核表达载体，有助于进一步研究朊蛋白N-糖基化修饰的生物学功能。定点突变野生型人朊蛋......
CD82/KAI1是四跨膜蛋白家族（tetraspanin superfamily）的重要成员之。其主要生物学功能是参与细胞运动、迁移的调节。CD82广泛表达于......
