METALLOPROTEINASES相关论文
Involvement of acid-sensing ion channel 1a in matrix metabolism of endplate chondrocytes under extra
Acidic conditions are present in degenerated intervertebral discs and are believed to be responsible for matrix breakdow......
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Lentinula edodes extract inhibits matrix metalloproteinase expression and increases typeⅠprocollagen
Objective:To determine the effect of Lentinula edodes extract on ultraviolet(UV)A and UVB-induced changes in matrix meta......
目的 探讨高压氧(HBO)对缺血再灌注小鼠脑组织中基质金属蛋白酶(MMPs)MMP-9、MMP-2 mRNA的表达及血脑屏障通透性的影响.方法 复制......
目的 检测肝病患者血清基质金属蛋白酶1(MMP-1)、基质金属蛋白酶抑制剂1(TIMP-1)、转化生长因子B1(TGF-β1)、透明质酸(HA)、Ⅲ型......
TIMP-3 gene transfection suppresses invasive and metastatic capacity of human hepatocarcinoma cell l
BACKGROUND:Tissue inhibitor of metalloproteinases (TIMPs) can restrain the tumor growth by their protein property and ma......
,Losartan inhibited expression of matrix metalloproteinases in rat atherosclerotic lesions and angio
AIM: To explore whether the angiotensin Ⅱ (Ang Ⅱ) receptor 1 (AT1) antagonist, losartan could reduce activity and expr......
目的 通过研究牙周基础治疗对伴动脉粥样硬化(atherosclerosis,As)慢性牙周炎(chronic periodontitis,CP)大鼠的影响,以期为临床提......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
目的 观察狼疮肾炎(LN)患者入院第一天及强的松治疗后血清基质金属蛋白酶MMP-9水平,并分析其规律.方法 用双抗体夹心ELISA法检测各......
目的 比较大鼠左半结肠和右半结肠吻合愈合的能力,为临床行结肠手术方式的选择提供理论依据.方法 将40只雄性Wistar大鼠随机分为A......
The regulating role of mutant IκBα in expression of TIMP-2 and MMP-9 in human glioblastoma multiform
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Metalloproteinases have a critical role in a broad spectrum of cellular processes ranging from the break-down of extrace......
The matrix metalloproteinases(MMPs) are a family of zinc-dependent endopeptidases originally characterized as secreted p......
Metalloproteinase expression after desflurane preconditioning in hepatectomies:A randomized clinical
BACKGROUND Hepatectomy with inflow occlusion results in ischemia-reperfusion injury;however,pharmacological precondition......
Production and activity of matrix metalloproteinases during liver fibrosis progression of chronic he
BACKGROUND Matrix metalloproteinases(MMPs)participate in the degradation of extracellular matrix compounds,maintaining t......
Metalloproteinases have a critical role in a broad spectrum of cellular processes ranging from the break-down of extrace......
目的:探讨皮肤鳞状细胞癌(SCC)转移病灶中基质金属蛋白酶(MMPs)的表达及其与basigin/CD147表达间的关系.方法:运用免疫组化法检测1......
基质金属蛋白酶（MMPs）是一类高度保守的锌离子依赖内肽酶家族，大部分能降解基底膜成分和细胞外基质，它在肿瘤的侵袭转移中起到了重要的......
目的探讨口腔鳞状细胞癌(oral squamous cell carcinoma,OSCC)组织中基质金属蛋白酶9(matrix metalloproteinase-9,MMP-9),基质金......
Structure,expression,and developmental function of early divergent forms of metalloproteinases in Hy
Metalloproteinases have a critical role in a broad spectrum of cellular processesranging from the break-down of extracel......
目的：探讨大鼠正畸牙周组织改建过程中基质金属蛋白酶－３（ＭＭＰ－３）和金属蛋白酶组织抑制因子－１（ＴＩＭＰ－１）与正畸牙齿移动的关系。方法：在ＳＤ成年大鼠上颌左侧第一......
Effects of cytokines, growth factors and drugs on matrix metalloproteinases activities of osteoarthr
Objective: To evaluate the effects of some cytokines, TGF-β1 and drugs on matrix metalloproteinases (MMPs) activities i......
目的探讨基质金属蛋白酶及其抑制因子在小儿先天性胆道闭锁肝组织中的表达及临床意义。方法采用免疫组织化学技术检测22例小儿先天......
目的：探讨阿托伐他汀早期强化治疗对急性心肌梗死（AMI）患者基质金属蛋白酶（MMP）和预后的影响。方法：将176例AMI患者分为他汀治疗组（阿托伐......
目的:研究紫杉醇对HO8910人卵巢癌细胞的体外杀伤作用;紫杉醇对MMP-2、MMP-9 mRNA表达的影响.方法:采用MTT法检测紫杉醇对HO8910细......
TIMP-3 gene transfection suppresses invasive and metastatic capacity of human hepatocarcinoma cell l
BACKGROUND:Tissue inhibitor of metalloproteinases (TIMPs)can restrain the tumor growth by their protein property and mat......
目的研究乳腺癌组织中金属蛋白酶组织抑制因子1（TIMP-1）的表达及其与增殖细胞核抗原ki67、P53癌基因（P53gene）、人表皮生长因子受体-2（H......
目的：研究胎盘绒毛滋养层细胞基质金属蛋白酶-9(MMP-9)的表达，探讨MMP-9在胎儿宫内发育迟缓（IUGR）发病中的作用。方法：用免疫组化两步法......
目的：探讨测定血清基质金属蛋白酶－9（MMP－9）的含量对诊断卵巢上皮癌的价值及它与患者预后的关系。方法：将卵巢上皮癌（OEC）43例，卵巢交界性肿......
目的:研究葡萄胎和先兆子痫等与滋养层细胞密切相关的妊娠疾病在病理发生机制上与膜型基质金属蛋白酶表达的关系.方法:采用逆转录......
目的：检测Ⅰ、Ⅲ和Ⅳ型胶原及相关的调控间质金属蛋白酶(MMPs)蛋白的表达，探讨子宫 颈鳞 状细胞癌细胞外间质(ECM)重构与癌细胞侵袭......
目的:探讨子宫内膜异位症患者在位及异位子宫内膜中基质金属蛋白酶-2、-9(MMP-2,MMP-9)的表达特点及在子宫内膜异位症发病机制中的......
目的:观察左甲状腺素 (L-thy) 诱导的大鼠肥大心肌中基质金属蛋白酶(MMPs)及其抑制剂(TIMPs)的基因表达和新内皮素受体拮抗剂CPU-0......
目的探讨基质金属蛋白酶-1(matrix.metalloproteinase-1,MMP-1)及其抑制剂金属蛋白酶组织抑制剂-1(tissue.inhibitor.of.metallopr......
目的观察冠心病患者支架置入术后基质金属蛋白酶-9（MMP-9）、P-选择素血清浓度的动态变化，比较常规支架术和直接支架术后MMP-9、P-选择......
背景:椎间盘髓核组织是人体易退变的组织,Ⅱ型胶原是髓核的主要成分,而基质金属蛋白酶8(MMP-8)可降解Ⅱ型胶原,引起组织退化。目的......
为探讨基质金属蛋白酶ＭＭＰ９及其抑制剂ＴＩＭＰ１在喉癌中表达的意义。我们采用免疫组化法对它们在３６例喉癌中的表达进行研究，结果显示：ＭＭＰ９有ＴＩＭＰ１的阳性表达率......
Effects of hypoxia, hyperoxia on the regulation of expression and activity of matrix metalloproteina
AIM To study the effects of hypoxia, hyperoxia on the regulation of expression and activity of matrix metalloproteinase-......
AIM To investigate the expression of annexin II in gastric carcinoma and its role in the metastasis of gastric cancer.ME......
目的探讨基质金属蛋白酶(Matrix metalloproteinases, MMP)-2,9在中耳继发性胆脂瘤中的表达及其临床意义.方法应用免疫组织化学技......
目的：探讨基质金属蛋白酶-2（MMP-2，72KD、62KD）的活性与乳腺癌侵润、转移的关系。方法：利用酶谱和计算机软件检测并分析了35例乳腺癌组......
Extracellular matrix plays an important role in maintaining organic structure and function, cellular proliferation and d......
目的:探讨血清、尿金属蛋白酶组织抑制因子-1(TIMP-1)浓度对肾脏纤维化的诊断价值.方法: 以酶联免疫吸附检测(ELISA)方法检测健康......
目的研究基质金属蛋白酶(MMPs)及其组织抑制剂(TIMP-1) 在大鼠慢性阻塞性肺疾病(COPD)模型气道和肺组织中的表达及其在细胞外基质......
目的:探讨雌激素对胎儿血管平滑肌细胞(HVSMC)基质金属蛋白酶-2(MMP-2)分泌及其活化的影响.方法:分别以不同浓度的雌二醇与体外培......
目的:研究基质金属蛋白酶在低O2高CO2性肺动脉高压中的作用.方法: 在慢性低氧高二氧化碳肺动脉高压大鼠模型上,采用图像分析、免疫......
目的探讨基质金属蛋白酶-2(matrix metalloproteinase-2,MMP-2)和组织金属蛋白酶抑制物-2(tissue inhibitor of metalloproteinase......
目的探讨β-链接素（β-catenin）和基质金属蛋白酶7（matrix metalloproteinase-7，MMP-7）表达与大肠癌侵袭转移的关系。方法应用组织芯片......
