HIPPOCAMPUS相关论文
目的:探讨芍药苷对醋酸铅诱导海马神经元凋亡的影响及潜在机制。方法:于2020年9月，从胎鼠中分离培养原代海马神经元细胞，并利用细胞......
目的:评价长期摄入ω-3多不饱和脂肪酸(ω-3 PUFAs)对术后认知功能障碍(POCD)小鼠海马小胶质细胞活化的影响。方法:清洁级健康雄性......
Adult hippocampal neurogenesis (AHN) facilitates hippocampal circuits plasticity and regulates hippocampus- dependent co......
Steroid hormones play important roles in brain development and function.The signaling of steroid hor-mones depends on th......
金纳米颗粒(GNPs),由于其具有良好的生物稳定性、独特的光电和物理化学特性,已被广泛用于纳米医学和神经科学.但是,不同形貌的GNPs......
Efficacy of quercetin,oleanolic acid,icariin on apoptosis and mito-gen-activated protein kinases sig
OBJECTIVE:To investigate the effect of quercetin,oleanolic acid,icariin and their compatibility on the apoptosis of hipp......
研究背景海马位于侧脑室颞角底部,外形如同海马而得名。人类的学习、认知和记忆等方面与大脑边缘系统密切相关,而海马是边缘系统重......
Phosphorylated tau as a toxic agent in synaptic mitochondria: implications in aging and Alzheimer &#
During normal aging, there is a decline in all physiological functions in the organism. One of the most affected organs ......
目的:分析颞叶癫痫患者海马区氢质子磁共振波谱(proton magnetic resonance spectroscopy，n 1H-MRS)代谢物与外周血T淋巴细胞......
Our previous study has shown that the transcription factor Krüppel-like factor 7 (KLF7) promotes peripheral nerve regen......
Estimation of the density of neural,glial,and endothelial lineage cells in the adult mouse dentate g
The dentate gyrus subregion of the mammalian hippocampus is an adult neural stem cell niche and site of lifelong neuroge......
During free exploration,the emergence of patterned and sequential behavioral responses to an unknown environment reflect......
The discovery that new neurons are produced in some regions of the adult mammalianbrain is a paradigm-shift in neuroscie......
Our previous studies have shown that glutamate and hippocampal neuron apoptosis are key signals and direct factors assoc......
The Relevance between Symptoms and Magnetic Resonance Imaging Analysis of the Hippocampus of Depress
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Neutroprotective Efficacy of Sodium Tanshinone B on Hippocampus Neuron in A Rat Model of Focal Cereb
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Icariin Improves Cognitive Impairment after Traumatic Brain Injury by Enhancing Hippocampal Acetylat
Objective: To examine the effect of icariin (ICA) on the cognitive impairment induced by traumatic brain injury (TBI) in......
ZNF804A Variation May Affect Hippocampal-Prefrontal Resting-State Functional Connectivity in Schizop
The ZNF804A variant rs1344706 has consistently been associated with schizophrenia and plays a role in hippocampal-prefro......
Role of the Hippocampus in Distinct Memory Traces: Timing of Match and Mismatch Enhancement Revealed
A previous functional magnetic resonance imaging study reported evidence for parallel memory traces in the hippocampus:a......
A Critical Time-Window for the Selective Induction of Hippocampal Memory Consolidation by a Brief Ep
Although extensively studied,the exact role of sleep in learning and memory is still not very clear.Sleep deprivation ha......
Huntington\'s disease (HD) is a neurodegenerative disease caused by a polyglutamine expansion in the huntingtin (Htt) ......
Antidepressant-Like Action of Single Facial Injection of Botulinum Neurotoxin A is Associated with A
The present study was designed to examine the therapeutic effects of Botulinum neurotoxin A (BoNT/A) on depression-like ......
Rho-associated kinases (ROCKs) are serinethreonine protein kinases that act downstream of small Rho GTPases to regulate ......
An enzyme-based MEA probe for second-by-second measurements of L-glutamate release and uptake in rat
L-glutamate(Glu)neurotransmitter plays a predominant role in the mammalian central nervous system,associated with normal......
Long-term ginsenoside administration prevents memory loss in aged female C57BL/6J mice by modulating
Memory impairment is considered to be one of the most prominent consequences of aging.Dete rioration of memory begins in......
Elevation of Synchronized Neuronal Activity in Hippocampal CA1 Accompanying Initial Storage of Assoc
Objective The hippocampus implements its function of initial memory consolidation on the basis of neuronal synchrony.Thu......
The retrieval of learned spatial memory and the acquisition of new spatial memory following temporar
There is widespread agreement that hippocampus plays a critical role in spatial memory.Recent selective lesions studies ......
The correlation between spatial navigation skills and hippocampal structural changes in APOE ε4 carr
Objective:Spatial navigation performance deficit is very common in Alzheimers disease patients,also,APOE is considered a......
Objective To investigate the shimming effect of PB and iterative VOI the hippocampus MRS and compare the spectra quality......
Objective Apolipoprotein E (APOE) and sortilin-related receptor (SORL1) genes act on the same metabolic pathway and asso......
Background:The aim of this study was to investigate the brain iron deposition in primary insomnia (PI) and its correlati......
Activation of matrix metalloproteinase in dorsal hippocampus drives improvement in spatial working m
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Objective Learning and memory is one of the most fundamental brain functions in the survival and development of human an......
Optogenetic activation of medial septal cholinergic neurons inhibits hippocampal ripple-related cell
Hippocampal CA1 sharp-wave ripples(100-250 Hz)is prominent oscillation during slow-wave sleep(SWS).It is thought to be c......
Virus-mediated deletion of Dnmt3a and Dnmt1 in the hippocampus impairs recognition memories in adult
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Objective: Thalamus and hippocampus have been found both involved in temporal lobe epilepsy,but how they interact during......
In this study,we exposed adult aged rats to a chronic variable stress model and compare astroglial changes as a function......
Interaction between hipocampus and thalamus in epileptic seizures induced by pilocarpine in mice Kan
Objective: The traditional view is that the thalamus plays an important role in generalized epilepsy,however,recent stud......
Long-term transcutaneous auricular vagus nerve stimulation suppresses seizure frequency and change n
Vagus nerve stimulation(VNS)has prominent anti-epilepsy effect on refractory epilepsy,while it is accompanied with side ......
Objective: The CA1 region of the hippocampus has been demonstrated as key brain zone in learning and memory.The direct e......
Agonists of sigma1-receptor,donepezil and PRE-084,rescue hippocampal long-term potentiation impaired
Donepezil is a potent acetylcholinesterase inhibitor used for the treatment of Alzheimers disease(AD)....
Accumulating evidence implicates the entorhinal cortex(EC),a core region in the limbic system,in pain modulation....
Functional dissection of the role of specific brain circuits in certain behaviors requires the direct monitoring of the ......
