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Challenges in the chemotherapy of Chagas disease: Looking for possibilities related to the differenc
Almost 110 years after the first studies by Dr. Carlos Chagas describing an infectious disease that was named for him, C......
Synthesis and Trypanocidal Evaluation of Some Novel 2-(Substituted Benzylidene)-5, 7-Dibromo-6-Hydro
Substituted 2-benzylidene-1-benzofuran-3-ones are commonly known as aurones. This class of bioactive heterocycles belong......
In this study, the essential oils extracted from the peels of Citrus aurantifolia, Citrus limon and Citrus sinensis were......
Trypanosoma cruzi(T.cruzi),the etiological agent of Chagas disease,affects nearly 18 million people in Latin America and......
Interferon-γ and other inflammatory mediators in cardiomyocyte signaling during Chagas disease cardi
Chagas disease cardiomyopathy(CCC), the main consequence of Trypanosoma cruzi(T.cruzi) infection, is an inflammatory car......
Antitrypanosomal Activity of a Semi-Purified Subfraction Rich in Labdane Sesquiterpenes, Obtained fr
In Brazil and several other Latin American countries, Chagas' disease still constitutes a serious medical and social......
American trypanosomiasis is a zoonosis of worldwide medical importance and currently there is no effective treatment in ......