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[会议论文] 作者：Dong Yu,Yuan Jin,Hongguang Ren,Mingda Hu,Wei Zhou,Long Liang,Junjie Yue,
来源：中国生物工程学会第十届学术年会暨2016年全国生物技术大会 年份：2016
Stenotrophomonas maltophilia(S.maltophilia) is a global multidrug-resistant human opportunistic pathogen in clinical environments which can cause serious human...
Gene flow,recombination,and positive selection in Stenotrophomonas maltophilia:mechanisms underlying
[会议论文] 作者：Dong Yu,Wei Zhou,Long Liang,Mingda Hu,Hongguang Ren,Yuan Jin,Junjie Yue,
来源：中国生物工程学会第十届学术年会暨2016年全国生物技术大会 年份：2016
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[会议论文] 作者：Zhiyi Zhang,Ming Liu,Beiping Li,Yuelan Wang,Junjie Yue,Long Liang,Jianzhong Sun,
来源：第七届国际分子模拟与信息技术应用学术会议 年份：2014
The SNP-158G＞A of KLK3 has been validated as a regulatory SNP (rSNP) by molecular biology assays, but the mechanism of how it affects the binding of an androgen receptor (AR) homodimer with DNA is unc...
[会议论文] 作者：Peng Du,Lei Xu,Weiyi Qiu,Dadi Zeng,Junjie Yue,Shuang Wang,Peitang Huang,Zhiwei Sun,
来源：第八届国际分子模拟与信息技术应用学术会议 年份：2016
Systemic lupus erythematosus(SLE)is a chronic,heterogeneous autoimmune disease short of effective therapeutic agents.A multitude of studies of SLE in the last decade have accentuated a central role of...
Diaminodiacid bridge improves enzymatic and in vivo inhibitory activity of peptide CPI-1 against bot
[期刊论文] 作者：Jintao Shen,Jia Liu,Shuo Yu,Yunzhou Yu,Chao Huang,Xianghua Xiong,Junjie Yue,Qiuyun Dai,
来源：中国化学快报（英文版） 年份：2021
The replacement of the disulfide bridge of CPI-1, a peptide inhibitor of light chain of Botulinum toxin serotype A, with the thioether-containing and biscarba-containing diaminodiacid bridge leads to a significant decrease in the degradatio......
Evaluation of a Recombinant Double Mutant of Staphylococcal Enterotoxin B (SEB-H32Q/K173E) with Enha
[会议论文] 作者：Liwei Gu,Junjie Yue,Yuling Zheng,Xin Zheng,Jun Wang,Yanzi Wang,Jianchun Li,Yongqiang Jiang,Hua Jiang,
来源：第七届国际分子模拟与信息技术应用学术会议 年份：2014
Background: Immunotherapy has been used to improve patient immune function, inhibit tumor growth and has become a highly promising method of cancer treatment.Highly agglutinative staphylococcin (HAS),...
Improving the Anti-Toxin Abilities of the CMG2-Fc Fusion Protein with the Aid of Computational Desig
[会议论文] 作者：Yongyi Xi,Xiaojie Wu,Lihua Gao,Yong Shao,Hui Peng,Hongxing Chen,Huipeng Chen,Xianwen Hu,Junjie Yue,
来源：第七届国际分子模拟与信息技术应用学术会议 年份：2014
CMG2-Fc is a fusion protein composed of the extracellular domain of capillary morphogenesis protein 2 (CMG2) and the Fc region of human immunoglobulin G;CMG2-Fc neutralizes anthrax toxin and offers pr...
[会议论文] 作者：Wei Zhou,Yan Li,Xichun Pan,Yuan Gao,Beiping Li,Zhengliang Qiu,Long Liang,Hong Zhou,Junjie Yue,
来源：第七届国际分子模拟与信息技术应用学术会议 年份：2014
Background: Toll-like receptor 9 (TLR9) recognises unmethylated CpG DNA and activates a signalling cascade, leading to the production of inflammatory cytokines such as TNF-α, IL-1, IL-6 and IL-12 via...
Leucine-rich Repeat 11 of Toll-like Receptor 9 Can Tightly Bind to CpG-containing Oligodeoxynucleoti
[会议论文] 作者：Xichun Pan,Chong Wu,Jiang Zheng,Hong Zhou,Junjie Yue,Guofu Ding,Bin Li,Xin Liu,Xinchuan Zheng,Mengchen,
来源：第七届国际分子模拟与信息技术应用学术会议 年份：2014
Background: Leucine-rich repeats (LRR) within the extracellular domain of human TLR9 (hTLRg) mediate binding to CpG ODN.Resultts: LRR11 ofhTLR9 has high affinity for CpG ODN, whereas the mutants of fi...
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