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[会议论文] 作者：Chuanzheng Zhou,
来源：第十一届全国化学生物学学术会议 年份：2019
The nucleosome is the basic structural repeating unit of chromatin which consists of double-stranded DNA(dsDNA)wrapping around a histone octamer core.In the...
Transesterification Reaction and the Repair of Embedded Ribonucleotides in DNA Are Suppressed in Nuc
[会议论文] 作者：Mengtian Ren,Chuanzheng Zhou,
来源：第十一届全国化学生物学学术会议 年份：2019
Ribonucleotides can be incorporated into DNA through many different cellular processes.Embedded ribonucleotides lead to genomic instability through spontaneous ribonucleotide cleavage via internal tra...
[会议论文] 作者：GuoceAn,Yingqian Zhang,Chuanzheng Zhou,
来源：中国化学会第十届全国化学生物学学术会议 年份：2017
Cysteine is especially attractive for site-specific chemical modification owing to its high nucleophilicity at physiological conditions and relatively low n...
Synthesis of Inositol Hexakisphosphate Deravatives to Study Hexakisphosphate-Dependent CRL-CSN Compl
[会议论文] 作者：ChuanlongZang,Chuanzheng Zhou,Feng Rao,
来源：中国化学会第十届全国化学生物学学术会议 年份：2017
Inositol hexakisphosphate(IP6)has been found to be associated with ubiquitination mediated protein degradation....
[会议论文] 作者：Xiaoping Zhou,Zhen Xi,Chuanzheng Zhou,
来源：第五届中国小核酸技术与应用学术会议 年份：2015
C4-AP is known to disrupt replication in E.coli and is a substrate for base excision repair[1][2].C4-AP is a major component of DNA damage produced by the a...
[会议论文] 作者：Chaochao Fan,Zhen Xi,Chuanzheng Zhou,
来源：第十一届全国化学生物学学术会议 年份：2019
C4′-modified ribonucleotides have recently attracted great interests.[1] C4′ modifications introduce stereoelectronic effect and thus modulate the conformation of the ribose,without losing the 2′-OH....
[会议论文] 作者：Fengmin Guo,Zhen Xi,Chuanzheng Zhou,
来源：中国化学会第十届全国化学生物学学术会议 年份：2017
Due to the specific properties of fluorine atom,such as small size,high electronegativity,carbon-fluorine bone strength and sensitivity of 19F NMR,the introduction of fluorine atom(s)into biomolecules...
[会议论文] 作者：Jing Bai,Yingqian Zhang,Zhen Xi,Chuanzheng Zhou,
来源：中国化学会第十届全国化学生物学学术会议 年份：2017
8-oxoguanine(8-oxo-G)is a major product of oxidative DNA damage.8-oxo-G is labile for further oxidation to produce OGox which is a strong electrophile and t...
[会议论文] 作者：Fengchao Li,Yingqian Zhang,Jing Bai,Zhen Xi,Chuanzheng Zhou,
来源：中国化学会第十届全国化学生物学学术会议 年份：2017
5-Formylcytosine(5fC)has been identified as a naturally occurring nucleobase and was initially thought to be merely an intermediate produced during DNA deme...
Thiol Specific and Tracelessly Removable Bioconjugation via Michael Addition to 5-Methylene Pyrrolon
[会议论文] 作者：Yingqian Zhang,Xiaoping Zhou,Yonghui Xie,Zhen Xi,Chuanzheng Zhou,
来源：中国化学会第十届全国化学生物学学术会议 年份：2017
Maleimide analogue,5-methylene pyrrolones(5MPs)are highly thiol-specific and tracelessly removable bioconjugation tools....
2-(2-azidoethyl)-2,5-di-(4,5-Dimethoxy-2-nitro-benzyloxy)-2,5-dihydr ofuran as a potential photoaffi
[会议论文] 作者：Jiahui Li,Mengdi Shang,Xiaoping Zhou,Zhen Xi,Chuanzheng Zhou,
来源：中国化学会第十届全国化学生物学学术会议 年份：2017
Photoaffinity crosslinking is widely used in biomolecules interaction studies....
[会议论文] 作者：Jing Bai,Fengchao Li,Yingqian Zhang,Zhen Xi,Chuanzheng Zhou,
来源：中国化学会第十届全国化学生物学学术会议 年份：2017
Nucleosome core particle(NCP)is the fundamental unit of genome DNA in eukaryotic cells.Recently studies have revealed that DNA damage and repair processes in NCP are much more complicated than in nati...
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