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[期刊论文] 作者：Yanna Zhu,Xiaokui Huo,Changyua,
来源：亚洲药物制剂科学(英文) 年份：2020
This study aimed to clarify that organic anion transporters(OATs)mediate the drug–drug interaction(DDI)between imipenem and cilastatin.After co-administration...
Sulfation of Melatonin: enzymatic characterization, differences of genders,organs and species, and b
[会议论文] 作者：Xiangge Tian,Xiaokui Huo,Baojian Wu,Xiaobo Wang,Chao Wang,Xiaochi Ma,
来源：2015第11届全国药物和化学异物代谢学术会议 年份：2015
Exogenous melatonin (Mel) is widely used in clinic for multiple therapeutic purposes.In metabolism pathways of Mel,6-hydroxymelatonin-sulfate (S-O-Mel) and N-acetylserotonin sulfate (S-NAS) are the mo...
A first highly selective probe for SULT2A1 activityin measurement of different biological samples ba
[会议论文] 作者：Weiru Jiang,Xiangge Tian,Xiaokui Huo,Chengpeng Sun,Chao Wang,Xiaochi Ma,
来源：第二届《药学学报》药学前沿论坛 年份：2016
Human cytosolsulfotransferase 2A1(SULT2A1)is a major metabolicenzyme isoform that mediates a sulfation reaction,which is a significant detoxification pathway for some endogenous and exogenous substrat...
[期刊论文] 作者：Fan Wu,Yu Zhang,Yanling Qiao,Ting Zhao,Baojing Zhang,Bangjiang Fang,Xiaokui Huo,Xiaochi Ma,
来源：亚洲传统医药 年份：2021
Jinhongtang is a traditional Chinese medicine formula composed of Rheum palmatum L.stem,Sargentodoxa cuneata stem,and Taraxacum mongolicum and is used for the treatment of sepsis.However,quality assessment method for Jinhongtang is not avai......
Herb-drug interaction prediction based on the quantitative structure-activity relationship (QSAR) of
[会议论文] 作者：Min Xu,Xiangge Tian,Peipei Dong,Xiaokui Huo,Chao Wang,Baojing Zhang,Shanshan Huang,Sa Deng,Xiaochi Ma,
来源：2015第11届全国药物和化学异物代谢学术会议 年份：2015
Object: The wide application of herbal medicines containing steroids and their saponins has resulted in the high risk of herb-drug interactions (HDIs)....
A highly selective fluorescent probe for real-time imaging of UDP-glucuronosyltransferase 1A8 in liv
[期刊论文] 作者：Mingyue Zhu,Zhenhao Tian,Lingling Jin,Xiaokui Huo,Chao Wang,Jingnan Cui,Yan Tian,Xiangge Tian,Lei Feng,
来源：化学科学与工程前沿 年份：2022
Uridine diphosphate(UDP)-glucuronosyl-transferases(UGTs)are enzymes involved in the biotrans-formation of important endogenous compounds such as steroids,bile acids,and hormones as well as exogenous substances including drugs,environmental ......
,Correlation analysis between the chemical contents and bioactivity for the quality control of Alism
[期刊论文] 作者：Xiaoxv Gao,Chengpeng Sun,Zhenglong Yu,Jian Cang,Xiangge Tian,Xiaokui Huo,Lei Feng,Xinguang Liu,Chao Wang,
来源：药学学报（英文版） 年份：2018
In order to clarify regions of production and to discriminate processing methods,quantitative and qualitative analyses for saccharides and terpenes in 35 batche...
[会议论文] 作者：Yonglei Cui,Jing Ning,Chao Wang,Peipei Dong,Guangbo Ge,Xiangge Tian,Jie Hou,Xiaokui Huo,Baojing Zhang,
来源：2015第11届全国药物和化学异物代谢学术会议 年份：2015
Objective Bufadienolides are a major class ofbioactive compounds derived from amphibian skin secretion.This work aim to characterize the sulfation of bufadienolides including conjugation position, the...
[期刊论文] 作者：Chao Wang,Peipei Dong,Yue An,Xinyu Zhao,Weiru Jiang,Gang Wang,Jie Hou,Lei Feng,Yan Wang,Guangbo Ge,Xiaokui Huo,
来源：药学学报（英文版） 年份：2018
Human cytosolic sulfotransferase 2A1 (SULT2A1) is an important phase Ⅱ metabolic enzyme.The detection of SULT2A1 is helpful for the functional characterization...
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