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[期刊论文] 作者：Renxiao Wang,
来源：黑龙江科技学院学报 年份：2013
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7...
[会议论文] 作者：Yu Du,Renxiao Wang,
来源：2019中国化学会第十五届全国计算(机)化学学术会议 年份：2019
In target-based drug design,a small molecule is designed to bind selected target(s)and makes a strong and enduring effect safely in vivo....
[会议论文] 作者：Guoqin Feng,Renxiao Wang,
来源：2019中国化学会第十五届全国计算(机)化学学术会议 年份：2019
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[会议论文] 作者：Qifan Yang,Renxiao Wang,
来源：2019中国化学会第十五届全国计算(机)化学学术会议 年份：2019
The Bcl-2 family consists of several proteins that share Bcl-2 homology(BH) domain and control apoptosis by governing mitochondrial outer membrane permeabilization(MOMP),which is a key step in the int...
Mining the Characteristic Patterns at the Protein-Protein Binding Interfaces and Its Potential Appli
[会议论文] 作者：Yan Li,Zhihai Liu,Renxiao Wang,
来源：第七届全国化学生物学学术会议 年份：2011
...
A Knowledge-Based Method for Estimating Desolvation Energy and Its Applications in Scoring Protein-L
[会议论文] 作者：Yan Li,Zhihai Liu,Renxiao Wang,
来源：第四届国际分子模拟大会(The International Conference on Molecular Simula 年份：2016
Desolvation energy is an important factor in the protein-ligand binding affinity prediction.However,on most of current scoring functions,it is often roughly...
[会议论文] 作者：Jie Li,Biao Yu,Renxiao Wang,
来源：2015年全国药物化学学术会议暨第五届中英药物化学学术会议 年份：2015
G protein-coupled receptor 119(GPR119)is a rhodopsin-like,class A Gs-coupled GPCR,which is predominately expressed in human pancreatic β-cells,where it mediates insulin secretion,and in gastrointestin...
[会议论文] 作者：Minyi Su,Yan Li,Renxiao Wang,
来源：第四届国际分子模拟大会(The International Conference on Molecular Simula 年份：2016
...
Mining the Characteristic Patterns at the Protein-Protein Binding Interfaces and Its Potential Appli
[会议论文] 作者：Yan Li,Zhihai Liu,Renxiao Wang,
来源：第七届全国化学生物学学术会议 年份：2011
...
Geometry-Dependent function for Calculating Hydrogen Bonding Energies on the Interactional Interface
[会议论文] 作者：Xiaonan Jiang,Guitao Wang,Zhanting Li,Renxiao Wang,
来源：第七届全国化学生物学学术会议 年份：2011
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An Efficient and Versatile Tool for Lead Structure Generation and Optimization in Structure-based Dr
[会议论文] 作者：Yan Li,Zhixiong Zhao,Zhihai Liu,Renxiao Wang,
来源：2015年全国药物化学学术会议暨第五届中英药物化学学术会议 年份：2015
In structure-based drug design,docking-based virtual screening is widely applied to lead discovery.Other types of methods,such as build-up methods,have to be employed in the subsequent lead optimizati...
Identification of Novel Lymphoid Tyrosine Phosphatase Inhibitors Using Pharmacophore-based and Docki
[会议论文] 作者：Xuben Hou,Renxiao Wang,Xiao Yu,Hao Fang,
来源：全国药物化学学术会议暨第四届中英药物化学学术会议 年份：2013
The lymphoid tyrosine phosphatase LYP,encoded by the PTPN22 gene,is a critical regulator of signaling in T cells.A single-nucleotide polymorphism(SNP)in the PTPN22 gene correlates with various autoimm...
Geometry-Dependent function for Calculating Hydrogen Bonding Energies on the Interactional Interface
[会议论文] 作者：Xiaonan Jiang,Guitao Wang,Zhanting Li,Renxiao Wang,
来源：第七届全国化学生物学学术会议 年份：2011
...
[会议论文] 作者：Yan Li,Xun Li,Wenge Zhong,Renxiao Wang,
来源：中国化学会第14 届全国计算(机)化学学术会议暨分子模拟国际论坛 年份：2017
G protein-coupled receptors(GPCRs)are still the largest target class in current drug discovery.Since 2007,with the great technology breakthroughs in GPCR crystallography,~150 GPCR complex structures h...
The PDBbind Database:A Comprehensive Collection of the Binding Data for the Biomolecular Complexes i
[会议论文] 作者：Zhihai Liu,Jie Li,Jiajie Li,Yan Li,Renxiao Wang,
来源：第七届全国化学生物学学术会议 年份：2011
...
[会议论文] 作者：Li Han,Zhihai Liu,Yan Li,Jie Li,Renxiao Wang,
来源：第十三届全国计算机化学学会会议 年份：2015
Biological macromolecular interactions form the basis of many essential processes in cellular activities.Molecular modeling methods can be used to detect sp...
[会议论文] 作者：Jie Liu,Zhihai Liu,Jie Li,Yan Li,Renxiao Wang,
来源：第十三届全国计算机化学学会会议 年份：2015
Molecular recognition between biological macromolecules and organic small molecules plays an important role in various life processes.Both structural inform...
[会议论文] 作者：Li-Ping Bai,Jie Liu,Li Han,Renxiao Wang,Zhi-Hong Jiang,
来源：中国化学会第29届学术年会 年份：2014
A comparative study on human telomeric DNA G-quadruplex binding of meso-5,10,15,20-tetrakis(N-methyl-4-pyridyl)porphyrin(TMPyP4)between its two salt forms,i.e.,tetratosylate and tetrachloride,was cond...
[会议论文] 作者：Zhixiong Zhao,Yuan Zhao,Yan Li,Zhihai Liu,Renxiao Wang,
来源：第十二届全国计算(机)化学学术会议 年份：2013
Docking-based virtual screening of large compound libraries has been widely applied to the early stage of lead discovery and is one of the most time-consuming steps in computer aided drug design.We ha...
[会议论文] 作者：Yan Li,Zhixiong Zhao,Zhihai Liu,Minyi Su,Renxiao Wang,
来源：中国化学会第十届全国化学生物学学术会议 年份：2017
In structure-based drug design,automated de novo design methods are helpful tools for lead discovery as well as lead optimization.In a previous study(J.Chem.Inf.Model.,2011,51,1474–1491),we reported a...
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