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Pharmacokinetic evaluation of a novel combined delivering double liposome system for enhancing thera
[会议论文] 作者：ZHAO Yanlei,HAO Haiping,LUO Dan,LI Juan,WANG Guangji,ZHOU Fang,
来源：第十届全国药物和化学异物代谢学术会议暨第三届国际ISSX/CSSX联合学术会议 年份：2012
Aim To construct a novel double liposome (DLP) formulation for combined delivery and evaluate the pharmacokinetic property of the new.system by in vitro and in vivo methods.Methods Doxorubicin (DOX) a...
[会议论文] 作者：WU Liang,GONG Ping,WU Yuzheng,LIAO Ke,Qi Qu,LIU Huiying,WANG Guangji,HAO Haiping,
来源：第十届全国药物和化学异物代谢学术会议暨第三届国际ISSX/CSSX联合学术会议 年份：2012
目的 以中药多组分制剂为例，建立复杂基质中非靶标同系物的快速鉴定方法。方法 首先根据图谱比对去除空白样品中基质的干扰；再借助已有标准品的碎裂规律，根据诊断离子介导的......
Metabolic profile, enzyme kinetics, and reaction phenotyping of β-lapachone metabolism in human live
[会议论文] 作者：CHENG Xuefang,ZHOU Xueyan,XIE Yang,QI Qu,LIU Fang,LIAO Ke,WANG Guangji,HAO Haiping,
来源：第十届全国药物和化学异物代谢学术会议暨第三届国际ISSX/CSSX联合学术会议 年份：2012
β-lapachone (β-Lap) is an NAD(P)H: quinone oxidoreductase 1 (NQO1) target anti-tumor drug candidate in phase Ⅱ clinical trials.The present study aimed to uncover the metabolic characteristics, enzyme...
Disturbance of hepatic and intestinal UDP-glucuronosyltransferase in rats with trinitrobenzene sulfo
[会议论文] 作者：ZHOU Xueyan,XIE Yang,QI Qu,CHENG Xuefang,LIU Fang,LIAO Ke,WANG Guangji,HAO Haiping,
来源：第十届全国药物和化学异物代谢学术会议暨第三届国际ISSX/CSSX联合学术会议 年份：2012
UDP-Glucucunosyltransferase (UGT) is an important class of phase Ⅱ metabolizing enzymes, playing a pivotal role in detoxifying various substances and in the pathological procedures of some diseases.Th...
Quantitative analysis of neurochemical panel in rat brain and plasma by liquid chromatography-tandem
[会议论文] 作者：ZHENG Xiao,KANG An,LIANG Yan,DAI Chen,XIE Tong,XIE Lin,PENG Yin,WANG Guangji,HAO Haiping,
来源：第十届全国药物和化学异物代谢学术会议暨第三届国际ISSX/CSSX联合学术会议 年份：2012
The dopamine, serotonin, and kynurenine metabolic pathways play pivotal roles on brain function and their disorders are closely related to various neurological diseases.Comprehensive measurement of th...
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