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阿普唑呛中毒,临床少见报导,现将笔者所遇一例,报告如下。 刁×,女,21岁,因服阿普唑呛90余片(0.4mg/片),神志不清12小时,于1992年8月29日急诊入院。入院查体:T37.2℃,P120次/分,R24次/分,BP816kPa,深昏迷,角膜及对光反射消失,瞳孔等大固定、约2mm,心肺(一),腹部略张气,肝脾未扪及,四肢冰凉、呈驰缓状态,各种深浅反射消失,未引出病理征。诊断为药物中毒伴休克。立即用清水彻底洗胃、未洗出明显药液。50％硫酸钠40ml导泻,20％甘露醇250mlql2h静推以促进药物排泄,多巴胺20mg加低右500ml静滴以维持血压,并同时补液、维持电解质平衡及预防感染。
Alprazole choke poisoning, clinical rare reports, now I encountered a case, the report is as follows. Diao ×, female, 21 years old, due to clothing alprazole choke more than 90 pieces (0.4mg / tablet), confusion 12 hours in August 29, 1992 emergency admission. Admission examination: T37.2 ℃, P120 beats / min, R24 beats / min, BP816kPa, deep coma, corneal and light reflex disappeared, pupils and other large fixed, about 2mm, cardiopulmonary (a) Spleen not palpable, cold limbs, was Chi slow state, a variety of depth reflex disappeared, did not lead to pathological sign. Diagnosis of drug poisoning with shock. Immediate gastric lavage with water, did not wash out the obvious liquid. 50% sodium sulfate 40ml catharsis, 20% mannitol 250mlql2h static push to promote drug excretion, dopamine 20mg lower right 500ml intravenous infusion to maintain blood pressure, and at the same time rehydration to maintain electrolyte balance and prevent infection.