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视网膜母细胞瘤是发生在幼儿眼内的一种恶性肿瘤,虽然有极少数患儿未经治疗而自然治愈,但绝大多数都因此而死亡。其发生率约为出生数的10000~34000:1。在日本,根据金子1975~1979年的调查,结果为15000:1,每年发生本病的约有100人,占眼球肿瘤死亡率的第一位。本病有遗传性,以常染色体显性遗传传给后代。过去,本病病例很少,但由于治疗技术的不断进步,一部分患儿被治愈而生存、结婚,因此遗传便成了一个非常重要的问题。类型与遗传本病有家族性早已被公认,其原始类型是1821年
Retinoblastoma is a type of malignancy that occurs in the eyes of young children. Although a small number of children naturally cure without treatment, the vast majority of them die. The incidence rate is about 10,000 to 34,000:1 of the number of births. In Japan, according to a survey conducted by Gold from 1975 to 1979, the result was 15,000:1. About 100 cases of this disease occur each year, accounting for the first place in eyeball tumor mortality. The disease is hereditary and transmitted to offspring by autosomal dominant inheritance. In the past, there were few cases of this disease, but due to the continuous advancement of treatment techniques, some children were cured and survived and married. Therefore, genetics has become a very important issue. Type and hereditary The disease is familial and has long been recognized. Its original type was 1821.