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目的观察复方甘草酸苷注射液联合利巴韦林治疗普通型儿童手足口病的临床疗效。方法将纳入符合标准的手足口病患儿随机分为治疗组及对照组各40例,两组均采用退热、补液等对症治疗,治疗组给予复方甘草酸苷注射液联合利巴韦林注射液治疗。对照组给予利巴韦林注射液治疗。两组治疗5d为1个疗程,观察2组患儿体温下降、皮疹消退情况。结果从体温下降、皮疹消退情况观察,统计资料显示,治疗组与对照组比较有显著性差异,(P<0.5)。结论复方甘草酸苷针联合利巴韦林治疗普通型儿童手足口病具有明显抗炎、退热、促进皮疹消退作用,值得推广应用。
Objective To observe the clinical efficacy of compound glycyrrhizin injection combined with ribavirin in treating common hand-foot-mouth disease in children. Methods Forty children with hand-foot-mouth disease were randomly divided into treatment group (40 cases) and control group (40 cases). Both groups were treated with antipyretic and fluid replacement therapy. The treatment group was given compound glycyrrhizin injection combined with ribavirin injection Liquid treatment. The control group was treated with ribavirin injection. Two groups of treatment for 5d for a course of treatment, observed two groups of children with hypothermia, rash subsided. Results From the temperature drop, rash subsided observation, statistical data show that the treatment group and the control group were significantly different (P <0.5). Conclusion Compound glycyrrhizin combined with ribavirin has obvious anti-inflammatory and antipyretic effects and can promote the eradication of rash in hand-foot-mouth disease of common children, which is worth popularizing and applying.