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目的探讨极低出生体重儿体重增长的影响因素。方法对2007年1月至2010年12月我院新生儿病区收治的极低出生体重儿进行回顾性分析。结果按出院时体重是否达同胎龄第10百分位分为体重增长正常组(A组)和体重增长迟缓组(B组),共52例入选。A组23例,B组29例。第2周A组的总热量高于B组,第2、3周A组的肠内热量高于B组,第1周A组氨基酸、脂肪乳的热卡高于B组,第3周A组体重高于B组。差异均有统计学意义(P<0.05)。A、B两组均数比较,胎龄分别为(32.57±1.78)周和(31.53±1.16)周,差异有统计学意义(P<0.05)。多元回归分析显示,胎龄及开始应用氨基酸日龄是影响体重增长的相关因素(P均<0.05)。结论出生时的胎龄是影响体重增长的因素之一,极低出生体重儿生后早期应用氨基酸有助于体重增长。
Objective To investigate the influencing factors of weight gain in very low birth weight infants. Methods Retrospective analysis of very low birth weight children admitted to neonatal ward in our hospital from January 2007 to December 2010. The results were divided into weight-normal group (group A) and weight-loss group (group B) according to the 10th percentile of gestational age at discharge, a total of 52 cases were enrolled. A group of 23 cases, B group of 29 cases. The total caloric value of group A was higher than that of group B in the second week. The caloric value of group A was higher than that of group B in the second and third weeks. The caloric scores of amino acids and fat emulsion in group A were higher than those in group B in the first week. Group body weight higher than the B group. The differences were statistically significant (P <0.05). The average age of group A and group B were (32.57 ± 1.78) weeks and (31.53 ± 1.16) weeks, respectively, with statistical significance (P <0.05). Multivariate regression analysis showed that gestational age and the age at onset of application of amino acids were the related factors of weight gain (P <0.05). Conclusion The gestational age at birth is one of the factors that affect the weight gain. The application of amino acids to the very low birth weight early in life helps to gain weight.