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5. Genome-wide detection of additional fetal chromosomal abnormalities by cell-free DNA testing of 15,6

Genome-wide detection of additional fetal chromosomal abnormalities by cell-free DNA testing of 15,6

来源 :中国科学:生命科学英文版 | 被引量 : 0次 | 上传用户：fengliguo1

【摘 要】

：

Cell-free DNA(cfDNA) testing for common fetal trisomies(T21, T18, T13) is highly effective. However, the usefulness of cfDNA testing in detecting other chromoso

【作 者】

：

Hong Yao Ya Gao Jia Zhao Rong 

【机 构】

：

DepartmentofGynecology&,Obstetrics,BGI-Shenzhen,ChinaNationalGeneBank,BirthDefectScreeningProject

【出 处】

：

中国科学:生命科学英文版

【发表日期】

：

2019年2期

【关键词】

：

CELL-FREE DNA GENOME-WIDE CHROMOSOMAL ABNORMALITIES sensitivity SPECIFICITY PPV 

【基金项目】

：

supported by the National Natural Science Foundation of China (81501264),Shenzhen Birth Defect Screening Project Lab (JZF No. [2016] 750),Shenzhen Municipal Government of China (JCYJ20150403101146312,

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Cell-free DNA(cfDNA) testing for common fetal trisomies(T21, T18, T13) is highly effective. However, the usefulness of cfDNA testing in detecting other chromosomal abnormalities is unclear. We evaluated the performance of cfDNA testing for genome-wide abn

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