目的探讨新生儿窒息与宫内巨细胞病毒（CMV）感染的关系。方法对窒息新生儿在生后1wk内进行血清CMV特异抗体IgM、IgC检测，部分病人同时送检脑脊液、尿、胃液找巨细胞包涵体、死亡病例进行病理检查。结果22例窒息新生儿中宫内CMV感染者16例，占72.73%．其力3例死亡。死亡病例经病理检查证实为全身性CMV感染。结论宫内CMV感染为窒息的原因之一。 Objective To investigate the relationship between neonatal asphyxia and intrauterine cytomegalovirus (CMV) infection. Methods Serum CMV specific IgM and IgC were detected within 1wk after birth in neonates with asphyxia. Some patients were also given cerebrospinal fluid, urine and gastric juice for giant cell inclusion bodies, and pathological examination was performed on the dead cases. Results Among the 22 asphyxiated neonates, 16 were CMV infected in the uterus, accounting for 72.73%. Its force was 3 deaths. Deaths confirmed by pathological examination of systemic CMV infection. Conclusion Intrauterine CMV infection is one of the causes of asphyxia.