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目的:评价补肾调轴方改善IVF-ET移植失败者或因子宫内膜薄而中断移植者子宫内膜容受性的临床疗效。方法:将39例行IVF-ET移植失败的患者和因子宫内膜薄而取消移植的患者作为研究对象,予补肾调轴方颗粒进行治疗,记录并观察治疗前后患者移植周期排卵日子宫内膜形态类型、种植日子宫内膜厚度以及子宫内膜血流灌注类型的改善情况。结果:治疗后子宫内膜厚度、形态类型以及血流灌注类型较治疗前均有改善,差异有统计学意义(P<0.05)。结论:中药补肾调轴方能增加子宫内膜厚度、改善子宫内膜形态和血流灌注类型,提高子宫内膜容受性,有助于胚胎的着床成功。
Objective: To evaluate the clinical effect of Bushen Tiaogan Fang on improving endometrial receptivity in patients with failed IVF-ET transplants or thin end-interrupted endometriosis. Methods: Thirty-nine patients with failed IVF-ET transplantation and patients with thin endarterectomy due to endometrial ablation were treated with “Bushen Tiaoshaofang Granule”. The changes of endometrial ovulation on the day of ovulation were recorded and observed before and after treatment Morphological type, endometrial thickness at implantation, and improvement of endometrial perfusion. Results: After treatment, the thickness of endometrium, the type of morphology and the type of blood perfusion were improved compared with before treatment, the difference was statistically significant (P <0.05). Conclusion: Bushenzhiazhao can increase the thickness of endometrium, improve the morphology of endometrium and the type of blood perfusion, improve the endometrial receptivity, and help the success of embryo implantation.