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由于面瘫多不导致死亡而没有很多机会实施尸体解剖,因此实验研究非常重要。本文介绍实验性面神经压榨后的退变和再生过程,利用两组动物从超微结构上进行分析。共用30只健康家兔,体重约1,500克,其中12只用于手术练习或对照,余下的18只进行研究。每个动物术前进行肌电图测定,麻醉后在无菌手术下将神经的颞外部分暴露。取直径0.25cm的特氟隆管用于压榨,此管紧紧包绕预先暴露的神经,再用两根丝线扎住。术后给予青霉素2日。动物分为两组,每组9只。为了研究退变过程,第一组是持续压榨,在这些动物中,任何时间均未看到肌电图上的活动。动物在3~90天杀死。第二组动物,压榨在10天后去除,6只动物在第3周观察到临床的和肌电图的恢复,在30~110天杀死。另3只无再生现象或再生很少,110~150天杀死。作者
Due to the fact that facial paralysis does not lead to death and there is not much chance of autopsy, experimental studies are very important. This article describes the degeneration and regeneration of the experimental facial nerve after crushing, using two groups of animals from the ultrastructure analysis. A total of 30 healthy rabbits shared a body weight of about 1,500 grams, of which 12 were used for surgical exercises or controls and the remaining 18 were studied. Electromyography was performed preoperatively in each animal, and the temporal portion of the nerve was exposed under aseptic surgery after anesthesia. Take a Teflon tube 0.25cm in diameter for squeezing, tightly wrapped around the nerves pre-exposed, and then use two wire Zhazhu. Postoperative penicillin 2 days. The animals were divided into two groups of nine. In order to study the degenerative process, the first group was continuous crush, in which animals no EMG activity was seen at any time. Animals kill in 3 to 90 days. The second group of animals, crushed removed after 10 days, 6 animals observed clinical and EMG recovery on week 3, and killed on days 30-110. The other three no regeneration or regeneration little, 110 to 150 days to kill. Author