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目的探讨Ｃ－反应蛋白（ＣＲＰ）和中性粒细胞碱性磷酸酶（ＮＡＰ）在儿童呼吸道感染病原学上的诊断价值。方法对５０例呼吸道细菌感染、５２例呼吸道病毒感染患儿及４８例健康对照组分别进行Ｃ－反应蛋白含量与中性粒细胞碱性磷酸酶阳性率和积分测定。结果呼吸道细菌感染组血液ＣＲＰ含量平均为６１．４±２．４μｇ／Ｌ，明显高于呼吸道病毒感染组９．６±４．４７μｇ／Ｌ和对照组（均小于１０μｇ／Ｌ）。且细菌感染组ＮＡＰ阳性率７７．５％、积分１７４．４，亦明显高于呼吸道病毒感染组。结论Ｃ－反应蛋白含量及中性粒细胞碱性磷酸酶活力在测定儿童呼吸道感染病原学上具有早期诊断价值，尤以ＣＲＰ为佳。
Objective To investigate the diagnostic value of C-reactive protein (CRP) and neutrophil alkaline phosphatase (NAP) in pediatric respiratory tract infection. Methods 50 cases of respiratory tract bacterial infection, 52 cases of respiratory virus infection in children and 48 healthy controls were detected C-reactive protein content and neutrophil alkaline phosphatase positive rate and integral determination. Results The mean CRP level in respiratory tract bacterial infection group was 61.4 ± 2.4μg / L, significantly higher than that of respiratory tract infection group 9.6 ± 4.47μg / L and control group (both less than 10μg / L). The positive rate of NAP in bacterial infection group was 77.5%, and the score was 174.4, which was also significantly higher than that of respiratory virus infection group. Conclusion C-reactive protein and neutrophil alkaline phosphatase activity in the determination of children with respiratory tract etiology early diagnostic value, especially CRP is better.