中医证候动物模型是中医药现代化的关键环节。现有证候模型实现了中医病因病机层面研究的突破,但忽略了体质与病证的相关性,导致了病证的多样化,难以体现中医证候的内涵。本课题组构想体质-病-证三位一体动物模型,通过体质因素和量表的引入,可纯化造模因素、控制病证多样化、量化诊断和评价体系,为中医证侯模型的科学化和标准化开创新的思路和方法。 TCM syndrome animal model is the key to the modernization of traditional Chinese medicine. The existing syndrome model has achieved a breakthrough in the etiology and pathogenesis of traditional Chinese medicine, but ignores the correlation between constitution and disease syndrome, leading to the diversification of syndromes and the difficulty of reflecting the connotation of TCM syndromes. The group conception of constitution - disease - card Trinity animal model, through the introduction of physical factors and scales, the model factors can be purified to control the disease syndrome diversification, quantitative diagnosis and evaluation system for the TCM syndrome model of the scientific and standardized Create new ideas and methods.