论文部分内容阅读
目的探讨未成熟血小板相关参数在幼儿缺铁性贫血(IDA)疾病中临床应用价值。方法采用XE-5000全自动血液分析仪检测温州地区63例健康幼儿外周血中未成熟血小板绝对值(IPF)、未成熟血小板比率、高荧光未成熟血小板比率、血小板平均侧向荧光强度(PLT-X)及网织血小板计数(PLT-O)。同期测定146例临床确诊的儿童IDA患者外周血的相同参数按贫血的严重程度划分,与对照组进行比较并做统计学分析。结果对照组PLT-、未成熟血小板比率、高荧光未成熟血小板比率、IPF、PLT-X参数男女之间差异均无统计学意义(P>0.05)。儿童IDA患者检测指标IPF、未成熟血小板比率、高荧光未成熟血小板比率及PLT-X指标与对照组比较,差异有统计学意义(P<0.01)。轻度IDA、中度IDA患者PLT-O指标与对照组比较,差异有统计学意义(P<0.01)。结论提示PLT相关新参数在IPF相关参数对临床IDA患者早期诊断和治疗有一定的价值。
Objective To investigate the clinical value of immature platelet-related parameters in young children with iron deficiency anemia (IDA). Methods The levels of immature platelet (IPF), immature platelet ratio, high fluorescence immature platelet ratio, platelet mean lateral fluorescence intensity (PLT-PCR) in peripheral blood of 63 healthy children in Wenzhou were detected by XE-5000 automatic blood analyzer. X) and reticulocyte count (PLT-O). In the same period, the same parameters of peripheral blood in 146 clinically diagnosed childhood children with IDA were divided according to the severity of anemia and compared with the control group for statistical analysis. Results There was no significant difference between male and female PLT-, immature platelet ratio, high fluorescence immature platelet ratio, IPF and PLT-X parameters in control group (P> 0.05). Compared with control group, the detection index of IPA, immature platelet, high fluorescence immature platelet and PLT-X in children with IDA were significantly different (P <0.01). The PLT-O index in mild IDA and moderate IDA patients was significantly higher than that in control group (P <0.01). The conclusion suggests that the new parameters related to PLT have certain value in the early diagnosis and treatment of IDA patients in IPF related parameters.