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目的：考察不同量活性炭对替硝唑葡萄糖注射液含量的影响以及不同ｐＨ时活性炭对注射液中替硝唑含量及ｐＨ值的影响。方法：注射液中分别加入不同量活性炭在８０℃水浴恒温３０ｍｉｎ后过滤，测替硝唑、葡萄糖含量。调整注射液为不同ｐＨ值，加入一定量活性炭同法操作，测替硝唑含量和ｐＨ值。结果：随活性炭用量的增加，注射液中替硝唑的含量明显降低，而葡萄糖的含量不受影响；ｐＨ值为４．０～５．０时，活性炭对替硝唑吸附相对较少，活性炭的加入注射液的ｐＨ值有所升高，当ｐＨ在４．０～５．０时影响不大，而ｐＨ在６．０～７．０时升高明显。结论：在实际生产工作中要根据活性炭的加入量酌情增大替硝唑的投入量；在不增加投入量的情况下，活性炭的用量宜控制在０．０５％左右，ｐＨ值宜控制在４．０～５．０之间
OBJECTIVE: To investigate the effect of different amounts of activated carbon on the content of tinidazole and glucose injection and the effect of activated carbon on the content of tinidazole and pH value in different pH. Methods: The injection of different amount of activated carbon were added to the water bath at 80 ℃ constant temperature 30min after filtration, measuring tinidazole, glucose content. Adjust the injection for different pH value, add a certain amount of activated carbon with the same operation, measuring tinidazole content and pH value. Results: With the increase of the amount of activated carbon, the content of tinidazole in the injection decreased obviously, while the content of glucose was not affected. When the pH value was 4.0-5.0, the adsorption of tinidazole to activated carbon was relatively less, The pH value of the added injection increased slightly when the pH was 4.0 ~ 5.0 little effect, while the pH increased significantly when 6.0 ~ 7.0. Conclusion: In actual production, the dosage of tinidazole should be increased according to the amount of activated carbon added. When the amount of tinidazole is not increased, the amount of activated carbon should be controlled at about 0.05% and the pH value should be controlled at 4 .0 ~ 5.0 between