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目的了解我院药品不良反应发生的特点及其引发的相关因素,为临床安全、合理用药提供依据。方法对该院2014年度收集上报的93例ADR报告进行回顾性分析。结果 ADR 93例,男性高于女性,50岁以上人群所占比例高于其他年龄段;引起ADR的因素以抗菌药物使用最高,占56.99%,其中又以β-内酰胺类居首,24例,占45.28%;损害器官、系统以皮肤及附件为主,引发ADR类型以一般药品不良反应为主,占94.62%。结论药品不良反应的发生与年龄、联合用药等因素有关,应加强ADR监测和报告工作,指导临床合理用药,减少药品不良反应的发生。
Objective To understand the characteristics of adverse drug reactions in our hospital and the related factors caused by them, providing the basis for clinical safety and rational drug use. Methods A retrospective analysis of 93 ADR cases collected and reported by the hospital in 2014 was conducted. Results 93 cases of ADR were higher in males than in females, and the proportion of people over 50 years old was higher than other age groups. The factors causing ADR were the highest use of antimicrobial agents, accounting for 56.99% , Accounting for 45.28%; damage to organs, the system mainly to the skin and accessories, lead to ADR type to the general adverse drug reactions, accounting for 94.62%. Conclusions The occurrence of ADRs is related to age, combination of drugs and other factors. ADR monitoring and reporting should be strengthened to guide clinical rational drug use and reduce adverse drug reactions.