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目的对比观察早期口服高浓度(33%)硫酸镁对急性胰腺炎预后的影响。方法对急性胰腺炎患者随机早期加用或不加用口服高浓度硫酸镁,对入选47例分为治疗组、对照组,对比统计观察其在各项指标方面的差异。结果治疗组腹痛缓解时间,腹部压痛消失时间、血尿淀粉酶恢复正常时间,明显短于对照组,重症急性胰腺炎发生率明显少于对照组。结论早期口服高浓度硫酸镁能显著改善急性胰腺炎预后及重症胰腺发生率。
Objective To compare the effect of early oral high concentration (33%) magnesium sulfate on the prognosis of acute pancreatitis. Methods Patients with acute pancreatitis were randomly divided into treatment group and control group randomly with or without oral high concentration of magnesium sulfate. The differences between the two groups in the indexes were observed. Results The pain relief time, abdominal tenderness disappearance time, hematuria amylase recovery time in the treatment group were significantly shorter than those in the control group. The incidence of severe acute pancreatitis was significantly less than that in the control group. Conclusion Early oral high concentration of magnesium sulfate can significantly improve the prognosis of acute pancreatitis and severe pancreas incidence.