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本实验观察了ＴＰＮ过程中表皮生长因子（ＥＧＦ）和谷氨酰胺（Ｇｌｎ）对肠道免疫功能的调节作用。结果显示，常规ＴＰＮ可导致血浆及各组织中Ｇｌｎ明显下降，肠粘膜淋巴细胞ＩＬ－２活性明显下降，细菌易位增高；而在ＴＰＮ过程中加用ＥＧＦ可防止肠道Ｇｌｎ水平下降；...
This experiment observed the role of epidermal growth factor (EGF) and glutamine (Gln) in the regulation of intestinal immune function during TPN. The results showed that conventional TPN could lead to a significant decrease of Gln in plasma and various tissues, a significant decrease of IL-2 activity in intestinal mucosal lymphocytes and an increase of bacterial translocation; and the addition of EGF during TPN prevented the decrease of intestinal Gln level. .