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目的观察静脉复合麻醉状态下大容量全肺灌洗术治疗肺泡蛋白沉着症的疗效。方法对20例诊断明确的肺泡蛋白沉着症患者行静脉复合麻醉下大容量全肺灌洗术,以临床症状严重程度、肺功能和动脉血气分析为观察对象,比较患者治疗前、后的各项指标。结果 20例肺泡蛋白沉着症患者大容量全肺灌洗术后,临床症状、肺功能及动脉血气分析结果较术前显著改善,差异有统计学意义(P<0.05)。结论通过大容量全肺灌洗术,患者病情在短期内得到显著改善,大容量全肺灌洗术是肺泡蛋白沉着症有效的治疗方法。
Objective To observe the curative effect of pulmonary vein lavage in the treatment of pulmonary alveolar proteinosis under intravenous anesthesia. Methods Twenty patients with definite pulmonary alveolar proteinosis underwent intravenous anesthesia with large-volume total lavage. The severity of clinical symptoms, pulmonary function and arterial blood gas analysis were used to compare the patients before and after treatment index. Results The results of clinical symptoms, pulmonary function and arterial blood gases in 20 patients with pulmonary alveolar proteinosis were significantly improved after large-volume total lavage. The difference was statistically significant (P <0.05). Conclusions The patient’s condition has been significantly improved in a short period of time through high-capacity whole-lung lavage. Large-volume total lavage is an effective treatment for pulmonary alveolar proteinosis.