发现和鉴定新型肝炎病毒一直是肝炎研究的热点之一。在2000年发现的SEN病毒被认为是一种新的肝炎病毒,最初的文献推测其可能与输血后非甲非戊型肝炎密切相关;但通过近两年的研究表明,其作为肝炎致病因子的地位有待进一步证实。本文从SEN病毒的基因组结构、检测方法、与肝炎的相关性和流行病学等方面重点介绍了其研究现状和所面临的问题。 Discovering and identifying new hepatitis viruses has long been one of the hot topics in hepatitis research. The SEN virus discovered in 2000 was considered as a new hepatitis virus. The initial literature suggests that it may be closely related to non-A non-E hepatitis after blood transfusion; however, it has been shown by past two years of studies that it acts as a causative agent of hepatitis The status to be further confirmed. This article focuses on the present situation and problems of SEN virus genome structure, detection methods, correlation with hepatitis and epidemiology.