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孤独症谱系障碍是一类发病于婴幼儿期的严重的神经发育障碍,发病率逐年增加,该病特征为社会沟通和社会交往障碍及受限制、重复性模式的行为模式,但导致这些症状的病因不明,寻找导致病症的潜在生物标志物有助于了解孤独症的病理机制,并有助于对疾病的早期诊断及早期干预。国内外已经在寻找生物学标记物方面进行了一些研究,本文对此做一综述,并展望未来的发展。
Autism Spectrum Disorder is a serious neurodevelopmental disorder that occurs in infancy with an increasing incidence, which is characterized by social communication and social interaction disorders and a pattern of restricted and repetitive patterns of behavior that lead to these symptoms The etiology is unknown. Finding potential biomarkers that can lead to the disorder helps to understand the pathological mechanisms of autism and contribute to the early diagnosis and early intervention of the disease. At home and abroad have been looking for biological markers in some research, this article to do a review, and look forward to the future development.