多系统器官衰竭已被确认为一临床综合征,其中肝功能衰竭是一重要组成部份,并由于其所引致的脓毒症和死亡率的增加而引人关注。最近,单核细胞-巨噬细胞所导致的实质组织的损害如肺、肾已被认为是某些系统功能紊乱的原因;由于肝细胞与具有吞噬作用的枯否氏细胞位置相近,这一机理很可能也参与多器官衰竭中 Multi-system organ failure has been identified as a clinical syndrome, with liver failure an important component and drawing attention due to the increased sepsis and mortality it causes. Recently, the damage of parenchymal tissue such as lung and kidney caused by monocyte-macrophages has been considered as the cause of some systemic dysfunction. Since liver cells are located close to the Phagocytic cells with phagocytosis, this mechanism It is also likely to be involved in multiple organ failure