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目的监测并分析我院Ⅰ类切口手术预防使用抗菌药物情况及合理性。方法随机抽取120例Ⅰ类切口手术患者病历,对其用药种类、用药时间、疗程、药物联用等情况进行统计分析。结果Ⅰ类切口手术预防使用抗菌药物率达100%,使用抗菌药物频度居前3位的为一代头孢(头孢唑啉29.1%)、其他β内酰胺类(头孢米诺及氨曲南15.8%)、二代头孢(头孢替安等15.2%)。单一用药占83.3%,二联用药占16.7%,无三联及三联以上用药。用药时间主要在术后(45%),最短3 d,最长20 d,平均用药时间8 d;术前0.5~2 h用药病例为37.5%。结论我院Ⅰ类切口手术预防用药单一用药率及初次给药时机的合理性明显上升,但仍然存在用药指征过宽、用药种类选择不当及疗程过长等问题,但仍需加强监管。
Objective To monitor and analyze the prevention and treatment of antimicrobial agents in class Ⅰ incision in our hospital. Methods A total of 120 patients undergoing type Ⅰ incision surgery were randomly selected for medical records, and the statistic analysis was made on the types of medication, the duration of medication, the course of treatment and the combination of drugs. Results The rate of antimicrobial agents was 100% for type Ⅰ incision surgery, cefazolin (29.1%) was the top three antibacterials, and 15.8% for other β - lactams (cefminox and aztreonam) ), Second-generation cephalosporins (cefotiam 15.2%). A single drug accounted for 83.3%, two drugs accounted for 16.7%, no triple and triple above medication. The duration of medication was mainly in the postoperative period (45%), the shortest 3 days, the longest 20 days, and the average medication time was 8 days. The preoperative 0.5 ~ 2 h medication was 37.5%. Conclusions The rationality of single-drug prophylaxis and the timing of primary drug administration in type Ⅰ incision surgeries in our hospital have obviously increased. However, there are still some problems such as too wide indications, inappropriate medication selection and long course of treatment. However, there is still a need to strengthen supervision.