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目的:探究2型糖尿病采用持续皮下胰岛素输注治疗的临床效果。方法:选取重庆市开县人民医院2012年10月-2014年5月收治的98例2型糖尿病患者,随机分为对照组和观察组,各49例。对照组采用餐前皮下注射胰岛素治疗,观察组采用胰岛素泵持续皮下输注治疗,观察两组患者血糖控制效果、胰岛素用量与治疗后低血糖发生率。结果:观察组血糖达标时间显著短于对照组(P<0.05),停止用药后血糖正常水平持续时间显著长于对照组(P<0.05),胰岛素用量显著少于对照组(P<0.05),观察组低血糖发生率低于对照组(P<0.05),差异均具有统计学意义。结论:持续皮下胰岛素输注治疗2型糖尿病效果好,且胰岛素用量少,安全性高。
Objective: To investigate the clinical effect of continuous subcutaneous insulin infusion therapy on type 2 diabetes mellitus. Methods: A total of 98 patients with type 2 diabetes treated in Kaixian People’s Hospital of Chongqing from October 2012 to May 2014 were randomly divided into control group and observation group, with 49 cases in each group. The control group was treated with subcutaneous insulin before meals, and the observation group was treated with continuous subcutaneous infusion of insulin pump. The effects of blood glucose control, insulin dosage and incidence of hypoglycemia after treatment were observed. Results: The blood glucose of the observation group was significantly shorter than that of the control group (P <0.05), and the duration of the normal blood glucose level was significantly longer than that of the control group (P <0.05). The insulin dosage was significantly less than that of the control group (P <0.05) Group hypoglycemia incidence was lower than the control group (P <0.05), the differences were statistically significant. CONCLUSION: Continuous subcutaneous insulin infusion is effective in treating type 2 diabetes mellitus, with less insulin dosage and high safety.