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目的:探讨间苯三酚对促进产程进展的临床效果及安全性。方法:选择2015年1月至2016年6月于中山市坦背医院产科分娩的1000例正常足月头位初产妇临床资料,依产程中用药方案不同分2组,按是否使用间苯三酚分2组,各组500例,观察组于产程中宫口开大3 cm时静注间苯三酚,对照组不予处理,对比两组间宫颈扩张情况、分娩情况、产后出血及围生儿结局。结果:观察组宫颈扩张速度比对照组明显快(P<0.05),用药-宫口开全时间即活跃期比对照组短(P<0.05);阴道分娩率87%高于对照组70.40%(P<0.05),两组产后2 h出血量、新生儿窒息率比较,差异均无统计学意义(P>0.05);观察组注药后未见不良反应。结论:间苯三酚可加快产程进展,促进阴道分娩,不增加出血量及新生儿窒息,未见母婴不良反应,安全性好。
Objective: To investigate the clinical effect and safety of phloroglucinol in promoting the progress of labor. Methods: From January 2015 to June 2016 in Zhongshan City, Tan back hospital Obstetric delivery of 1000 cases of normal full-term first-term primipara clinical data, according to the production program in different sub-2 groups, according to whether the use of phloroglucinol Divided into 2 groups, each group of 500 cases, the observation group in the labor process in the cervix 3 cm open intravenous phloroglucinol, the control group did not deal with cervical dilatation between the two groups, childbirth, postpartum hemorrhage and perinatal Children’s ending. Results: The cervical dilation rate in the observation group was significantly faster than that in the control group (P <0.05). The duration of the cervix - cervix cervix was shorter than that in the control group (P <0.05), vaginal delivery rate was 87% higher than that in the control group (70.40% P <0.05). There was no significant difference in bleeding volume and neonatal asphyxia rate between the two groups at 2 h postpartum (P> 0.05). No adverse reaction was observed in the observation group after injection. Conclusion: Phloroglucinol can accelerate the progress of labor and promote vaginal delivery, without increasing the amount of bleeding and neonatal asphyxia, no maternal and child adverse reactions, good safety.