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目的 探讨乳腺导管内乳头状瘤 (intraductalpapillomas ,IP)癌变的临床表现、生物学行为、诊断、治疗及预后。方法 对 1980年 1月至 2 0 0 1年 12月间 7例IP癌变病人临床资料进行回顾性分析。结果 7例IP癌变占同期 113例IP的 5 19%,术前均未能确诊 ,5例术中冰冻考虑IP癌变。结论 IP有癌变潜能 ,其癌变者术前确诊困难 ,术中冰冻对诊断治疗意义重大 ,应重视术后随访。
Objective To investigate the clinical manifestations, biological behavior, diagnosis, treatment and prognosis of intraductal papilloma (IP) canceration. Methods The clinical data of 7 patients with IP canceration between January 1980 and December 2001 were analyzed retrospectively. Results IP carcinomas in 7 cases accounted for 51.9% of 113 cases of IP in the same period, none of them was diagnosed before operation, and 5 cases were considered IP frozen in operation. Conclusions IP has the potential of canceration, and its cancerous patients are difficult to diagnose before surgery. Intraoperative freezing is of great significance to the diagnosis and treatment, and should be followed up after operation.