缩氨基硫脲及其环化产物噻二唑的合成及其活性

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合成了两个缩氨基硫脲及其两个环化产物———1,3,4-噻二唑,考察了噻二唑杂环的闭合条件,测定了产物的部分物理常数及红外光谱,对化合物作了初步抑菌活性筛选。为含有碳氮硫活性中心的金属螯合配体的研究提供了基础 Two thiosemicarbazones and two cyclized products - 1,3,4-thiadiazoles were synthesized. The closed conditions of the thiadiazoles were investigated. Some physical constants and infrared spectra of the thiadiazoles were determined. The compounds were initially screened for antibacterial activity. It provides a basis for the study of metal chelate ligands containing active carbon and nitrogen sulfur centers
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