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白色脂肪组织具有重要的内分泌功能,由它产生众多的细胞因子和炎症因子通过内分泌、旁分泌和自分泌的途径广泛影响机体物质和能量代谢过程、参与炎性反应、引起以代谢综合征、2型糖尿病为代表的胰岛素抵抗相关疾病的发生。本文对脂联素、抵抗素、瘦素、肿瘤坏死因子α、白细胞介素6、C反应蛋白等近年几个热点的脂肪细胞因子与胰岛素抵抗之间关系的研究进行综述,为临床的预防、诊断和治疗提供参考。
White adipose tissue has an important endocrine function, which produces a large number of cytokines and inflammatory factors through the endocrine, paracrine and autocrine pathways widely affect the body material and energy metabolism process, involved in inflammatory reactions, causing metabolic syndrome, 2 Type of diabetes as the representative of the occurrence of insulin resistance-related diseases. This review summarizes the recent studies on the relationship between adipokines and insulin resistance such as adiponectin, resistin, leptin, tumor necrosis factor alpha, interleukin 6 and C-reactive protein in recent years. In this paper, Diagnosis and treatment for reference.