论文部分内容阅读
目的：了解含铂药物化疗前后血电解质的变化及其规律。方法：对２８例病人在化疗前２４～４８ｈ及化疗后４８～７２ｈ，采集静脉血２ｍｌ，测定钾、钠、氯、钙的水平。结果：化疗前后血钾及血氯有明显变化（Ｐ＜００５），即化疗后血钾、氯明显降低，而血钠、钙无明显变化。结论：ＰＣ方案化疗期间，每ｄ至少应补充钾２ｇ，氯化钠９ｇ，化疗后根据电解质检查结果，调整补液类型和总量。
Objective: To understand the changes and regularities of blood electrolytes before and after chemotherapy with platinum-containing drugs. Methods: 28 patients were treated with 2 ml venous blood 24 to 48 hours before chemotherapy and 48 to 72 hours after chemotherapy. The levels of potassium, sodium, chloride, and calcium were measured. Results: There was a significant change in blood potassium and blood chlorine before and after chemotherapy (P<005), ie, blood potassium and chlorine were significantly reduced after chemotherapy, but no changes were observed in serum sodium and calcium. Conclusion: During the chemotherapy period of PC regimen, at least 2 g of potassium and 9 g of sodium chloride should be supplemented per d. After chemotherapy, the type and amount of fluid replacement should be adjusted according to the results of electrolyte examination.