论文部分内容阅读
目的探讨乌司他丁联合连续性血液滤过治疗重症加强护理病房(ICU)多脏器功能障碍综合征的疗效。方法 66例ICU多脏器功能障碍综合征患者,将其按照治疗措施的不同分为观察组和对照组,各33例。观察组采取乌司他丁联合连续性血液滤过治疗,对照组患者只进行连续性血液滤过治疗,对比两组患者的治疗效果。结果经治疗,观察组患者血肿瘤坏死因-α、白细胞介素6、8和循环内皮细胞等控制情况显著优于对照组,两组比较差异有统计学意义(P<0.05)。结论乌司他丁联合连续性血液滤过治疗ICU多脏器功能障碍综合征患者,可有效清除患者血液中所含炎症因子,对患者血管内皮形成保护性作用,值得在临床上推广使用。
Objective To investigate the efficacy of ulinastatin combined with continuous hemofiltration in the treatment of multiple organ dysfunction syndrome in intensive care unit (ICU). Methods 66 cases of ICU patients with multiple organ dysfunction syndrome, according to the different treatment measures were divided into observation group and control group, 33 cases in each. The observation group was treated with ulinastatin combined with continuous hemofiltration, while the control group only with continuous hemofiltration, the treatment effect was compared between the two groups. Results After treatment, the control of hematological tumor necrosis factor-α, interleukin 6, 8 and circulating endothelial cells in the observation group was significantly better than that of the control group. There was significant difference between the two groups (P <0.05). Conclusion Ulinastatin combined with continuous hemofiltration in patients with ICU multiple organ dysfunction syndrome can effectively remove inflammatory cytokines contained in the blood of patients, forming a protective effect on the vascular endothelial cells, which is worth popularizing in clinic.