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采用双抗体夹心法，检测了26例风湿热患儿的血清白细胞介素6、8（IL—6、8）的水平，分别为71．38±5．81ng／L和129．78±5．06ng／L，均明显高于正常对照组（P＜0．001）。CRP正常者8例中有5例IL－6增高。提示风湿病患儿IL－6、8水平明显增高，IL－6水平比CRP更能反应风湿热的活动程度。
Serum interleukin 6,8 (IL-6,8) levels were measured in 26 rheumatic fever children by double antibody sandwich method, which were 71.38 ± 5.81ng / L and 129.78 ± 5 respectively. 06ng / L, were significantly higher than the normal control group (P <0.001). IL-6 was elevated in 5 of 8 patients with normal CRP. The level of IL-6,8 in children with rheumatism was significantly higher, and the level of IL-6 was more responsive to CRP than rheumatic fever.