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目的探讨急性心肌梗死伴心力衰竭患者采用主动脉内球囊反搏辅助介入治疗的临床效果。方法选取2013年1月—2016年8月期间杭州师范大学附属医院收治的80例急性心肌梗死伴心力衰竭患者作为研究对象,采取单盲随机分组法将患者分为2组,每组40例。对照组患者实施介入治疗,观察组在对照组基础上实施主动脉内球囊反搏治疗。统计2组患者的临床总有效率、心脏血流恢复情况、血流动力学指标、N末端脑钠肽原(NT-pro BNP),采用统计学软件对2组数据进行分析,进而探讨急性心肌梗死伴心力衰竭患者采用主动脉内球囊反搏辅助介入治疗的临床效果。结果观察组的临床总有效率为90.00%,明显高于对照组的70.00%,差异有统计学意义(P<0.05)。观察组治疗后TIMI血流3级占比明显高于对照组,差异有统计学意义(P<0.05)。治疗前,2组患者的左心射血分数(LVEF)、每搏输出量(SV)、NT-pro BNP比较差异无统计学意义(P>0.05),治疗后2组患者的LVEF、SV、NT-pro BNP比较差异具有统计学意义(P<0.05)。结论在介入治疗基础上对急性心肌梗死伴心力衰竭患者实施主动脉内球囊反搏治疗可有效改善患者的心功能、血流动力学,有利于改善预后。
Objective To investigate the clinical effect of interventional aortic balloon pump in patients with acute myocardial infarction and heart failure. Methods Eighty patients with acute myocardial infarction and heart failure admitted to the Affiliated Hospital of Hangzhou Normal University from January 2013 to August 2016 were selected as the study subjects. The patients were divided into two groups (40 in each group) by single-blind randomization. Patients in the control group were treated with interventional therapy. The observation group was treated with intra-aortic balloon pump on the basis of the control group. The clinical total efficiency, cardiac blood flow recovery, hemodynamic indexes and N-terminal pro-brain natriuretic peptide (NT-pro BNP) were calculated in two groups of patients. Statistical data were used to analyze the two groups of data, The clinical effect of intra-aortic balloon pump in interventional therapy for patients with infarction and heart failure. Results The total clinical effective rate in the observation group was 90.00%, which was significantly higher than that in the control group (70.00%), the difference was statistically significant (P <0.05). The TIMI grade 3 in the observation group was significantly higher than that in the control group (P <0.05). Before treatment, LVEF, SV and NT-pro BNP showed no significant difference between the two groups (P> 0.05). After treatment, LVEF, SV, The difference of NT-pro BNP was statistically significant (P <0.05). Conclusion Intra-aortic balloon pump is effective in improving cardiac function and hemodynamics in patients with acute myocardial infarction and heart failure on the basis of interventional therapy, which is beneficial to improve prognosis.