以4-溴苯甲酸为原料,经过Curtius重排反应制得4-溴苯异氰酸酯,再进一步与3-氨基-1H-1,2,4-三氮唑发生亲核加成反应,合成了目标产物1-(4-溴苯基)-3-(1H-1,2,4-三氮唑-3-基)脲。对产物进行了元素分析,以红外、核磁和紫外光谱确认其结构;生测结果表明该化合物具有一定的植物生长调节活性。 4-Bromobenzoic acid was used as a starting material to make 4-bromobenzene isocyanate through Curtius rearrangement reaction and further nucleophilic addition reaction with 3-amino-1H-1,2,4-triazole to synthesize target The product 1- (4-bromophenyl) -3- (1H-1,2,4-triazol-3-yl) urea. The product was analyzed by elemental analysis, and its structure was confirmed by infrared, nuclear magnetic and ultraviolet spectroscopy. The results of bioassay indicated that the compound had certain plant growth regulatory activity.