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目的:探索医科院校学生完美主义、自动思维和抑郁之间的关系，为改善学生负性情绪提供建议。方法:使用Frost多维完美主义量表、自动思维量表及贝克抑郁量表对某医科院校的335名本科生展开调查并分析。结果:非适应性完美主义与自动思维、抑郁均正相关(n r＝0.42～0.47，n P<0.01)，自动思维与抑郁正相关(n r＝0.69，n P<0.01)。自动思维在非适应性完美主义与抑郁之间起中介作用，中介效应占总效应的比值为64.9%。自动思维在适应性完美主义与抑郁之间不起中介作用。n 结论:自动思维在非适应性完美主义和抑郁之间起中介作用，提示可以从认知方面改善学生的抑郁情绪。","Objective:To explore the relationships between the perfectionism, automatic thoughts and depression in medical university students, to provide suggestions for improving students negative emotions.Methods:The questionnaire including the Frost Multidimensional Perfectionism Scale, Automatic Thoughts Questionnaire and Beck Depression Inventory, was administrated among 334 students.Results:Depression were significantly and correlated with automatic thoughts and perfectionism(except for the organized dimension), while automatic thoughts positively related to depression(n r=0.42~0.47, n P<0.01). Students automatic thoughts had mediating effect between maladapitive perfectionism and depression (n r=0.69, n P<0.01), the ratio of mediating effect to total effect was 64.9%.n Conclusions:The effect of perfectionism on depression is partially mediated by automatic thoughts.This will provide a new perspective on depression intervention for maladaptive perfectionists.