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本文对150例乙型肝炎患者及HBsAg携带者用聚乙二醇沉淀物组份分析法进行了循环免疫复合物(CIC)检测。发现:(1)所检测的CIC与HBsAg及抗-HBs的存在有明显的相关关系,具有一定的特异性;(2)CIC在慢性活动性肝炎与肝炎后肝硬化的发病中起重要作用。我们认为CIC的检测,对乙型肝炎的诊断、临床分型及预后判断都有一定的考参意义。
In this study, circulating immunocomplex (CIC) was detected in 150 patients with hepatitis B and HBsAg carriers using polyethylene glycol precipitation assay. It is found that: (1) The detected CIC has a significant correlation with the existence of HBsAg and anti-HBs, and has certain specificity; (2) CIC plays an important role in the pathogenesis of chronic active hepatitis and posthepatitic cirrhosis. We think CIC testing has certain significance for the diagnosis, clinical classification and prognosis of hepatitis B.