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本报讯(通讯员孙国根记者刘金)复旦大学附属肿瘤医院胰腺外科虞先濬教授、王文权博士的一项最新研究发现,胰腺癌患者术后肿瘤标本中CD15、CD206、CD117分子免疫标记和Smad4突变基因的表达状态与患者总生存和无复发生存独立相关,肿瘤微环境或可用于预测胰腺癌术后患者的预后情况。论文6月3日在线发表于《英国外科学杂志》(Br J Surg)。
A new study by Professor Wang Xianquan and Professor Yu Xianjun, Department of Pancreatic Surgery, Affiliated Tumor Hospital of Fudan University found that CD15, CD206 and CD117 molecular immunolabeling and Smad4 mutations in postoperative tumor specimens of patients with pancreatic cancer The expression status of the gene is independently associated with the overall survival and recurrence-free survival of patients, and the tumor microenvironment may be used to predict the prognosis of postoperative patients with pancreatic cancer. The paper was published online June 3 in Br J Surg.