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目的:探讨胃肝样腺癌及普通型胃癌p21基因蛋白产物表达情况,进一步判断肿瘤的恶性程度。方法:应用免疫组化ABC法,对28例胃肝样腺癌进行检测。结果:28例胃肝样腺癌p21基因表达阳性率96.4%,其中染索状18例,团块状10例。其阳性表达明显高于普通型胃癌。结论:检查胃肝样腺癌p21基因蛋白产物表达,为临床治疗及判断预后提供重要依据
Objective: To investigate the expression of p21 gene protein in gastric adenocarcinoma of gastric and hepatocellular carcinoma and to evaluate the malignant degree of tumor. Methods: Using immunohistochemical ABC method, 28 cases of gastric adenocarcinoma were detected. Results: The positive rate of p21 gene expression was 96.4% in 28 cases of gastric adenocarcinoma, including 18 cases of stained cord and 10 cases of clumps. The positive expression was significantly higher than ordinary gastric cancer. Conclusion: The expression of p21 gene protein in gastric adenocarcinoma of the stomach and the liver can be analyzed. It provides an important basis for clinical treatment and prognosis