药物间的相互作用是改变药物在人体中反应的重要因素之一。本文介绍在用氨苯砜(dapsone)治疗前后的正常人及麻风病患者中阿斯匹林和氯霉素的药代动力学。试验用两组人进行。一组是16名(10男6女)健康志愿者,平均年龄及体重分别为42.7±2.5岁和55.2±2.9kg。试验前进行血压、脉率、体温及生物化学和血液学检查 The interaction between drugs is one of the important factors to change the reaction of drugs in the human body. This article describes the pharmacokinetics of aspirin and chloramphenicol in normal and leprosy patients before and after dapsone treatment. Experiment with two groups of people. One group consisted of 16 healthy volunteers (10 males and 6 females) with mean age and weight of 42.7 ± 2.5 years and 55.2 ± 2.9 kg, respectively. Before the test, blood pressure, pulse rate, body temperature and biochemistry and hematology examination