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目的:观察硒联合抑亢丸、甲巯咪唑治疗桥本甲状腺炎性甲亢的临床效果。方法:将2013年6月至2014年6月收治的160例桥本甲状腺炎性甲亢患者随机分为甲、乙、丙、丁四组,各40例,甲组接受甲巯咪唑治疗,乙组接受甲巯咪唑联合抑亢丸治疗,丙组接受硒联合甲巯咪唑治疗,丁组接受硒联合抑亢丸、甲巯咪唑治疗。分别观察各组的临床治疗效果。结果:乙组和丁组治愈率明显高于甲组和丙组,组间比较差异具有统计学意义(P<0.05),四组患者经治疗,突眼症状明显减轻,与治疗前比较差异具有统计学意义(P<0.05),乙组和丁组突眼症状改善情况好于甲组和丙组,组间比较差异具有统计学意义(P<0.05)。四组患者治疗期间均未见明显不良反应。结论:硒联合抑亢丸、甲巯咪唑治疗桥本甲状腺炎性甲亢效果显著,可调节机体免疫。
Objective: To observe the clinical efficacy of selenium combined with Yikang pills and methimazole in treating Hashimoto’s thyroiditis with hyperthyroidism. Methods: A total of 160 Hashimoto’s thyroiditis patients with hyperthyroidism admitted from June 2013 to June 2014 were randomly divided into four groups (A, B, C and D), 40 cases in each group, Group A received methimazole treatment, Group B Received methimazole combined with Yikang pill treatment, group C received selenium combined with methimazole treatment, group received selenium joint inhibition group, methimazole treatment. The clinical effects of each group were observed. Results: The cure rates of group B and group D were significantly higher than those of group A and group C. The differences between the groups were statistically significant (P <0.05). After treatment, the symptoms of the four groups were significantly relieved Statistically significant (P <0.05). The improvement of exophthalmos symptoms in groups B and D was better than that in groups A and C. The difference between the two groups was statistically significant (P <0.05). Four groups of patients during the treatment showed no significant adverse reactions. Conclusion: Selenium combined with Yokening pill, methimazole treatment of Hashimoto’s thyroiditis hyperthyroidism effect is significant, can regulate body immunity.