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目的探讨青少年甲状腺癌的临床病理特点、外科手术方式及预后。方法41例患者均采用手术治疗,辅以内分泌治疗,4例术后~(131)Ⅰ内照射治疗。结果术后病理:乳头状腺癌33例(80.5%),滤泡状腺癌8例(19.5%)。颈部淋巴结阳性者28例(68.3%),肺转移4例。40例获5年以上随访,1例失访,5年生存率95.1%(39/41),20例获10年以上随访,10年生存率90.0%(18/ 20)。结论青少年甲状腺癌颈部肿块临床表现大多数无特异性,难以与其他颈部肿块鉴别,易误诊。治疗手段以手术为主,预后良好。具体治疗方案应根据病理类型、肿瘤范围及转移情况决定。
Objective To investigate the clinicopathological features, surgical methods and prognosis of adolescent thyroid cancer. Methods Thirty-one patients were treated by surgery, supplemented by endocrine therapy, and 4 cases treated with ~ (131) Ⅰ internal irradiation. Results Postoperative pathology: papillary adenocarcinoma in 33 cases (80.5%), follicular adenocarcinoma in 8 cases (19.5%). Cervical lymph node positive in 28 cases (68.3%), lung metastases in 4 cases. Forty patients were followed up for more than five years. One patient lost follow-up and the 5-year survival rate was 95.1% (39/41). 20 patients were followed up for more than 10 years. The 10-year survival rate was 90.0% (18/20). Conclusion Most of the clinical manifestations of cervical cancer in young patients with thyroid cancer are nonspecific and difficult to identify with other cervical masses and are easily misdiagnosed. Surgical treatment-based, good prognosis. The specific treatment plan should be based on the type of pathology, tumor size and metastasis decisions.