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约5％～7％结直肠癌(CRC)病人有多个原发性病灶。其在老年病人的情况尚不明确。此研究调查老年手术病人及尸检者中多发性CRC的形式和分布。 病人和方法:收集1975～1998年东京板桥区某老年病院收治的947例≥65岁作手术的CRC病人和同时期≥65岁有CRC的362例尸检者的资料。比较不同年龄组(65～74岁,75～84岁和≥85岁组)的临床病理因素。 结果:947例手术病例中81例(8.6％)有2或3个CRC,(70例2个CRC,11例3个CRC),866例(91.4％)仅有1个CRC。362例尸检者中34例(9.4％)有多个CRC(26例2个,7例3个,1例4个)。手术病例中,3个年龄组有单个及多个CRC的男女比率相似;都是在65～74岁组中男性多于女性,
About 5% to 7% of patients with colorectal cancer (CRC) have multiple primary lesions. Its situation in elderly patients is not clear. This study investigated the form and distribution of multiple CRC in elderly surgical patients and autopsies. Patients and Methods: We collected data on 947 CRC patients aged 65 years or older and 362 individuals aged 65 years or older who had CRC at the same period from 1975 to 1998 in an elderly hospital in Itabashi, Tokyo. The clinical and pathological factors of different age groups (65-74 years old, 75-84 years old and 85 years old group) were compared. Results: Of the 947 surgical cases, 81 (8.6%) had 2 or 3 CRC (70 2 CRC, 11 3 CRC) and 866 (91.4%) had only 1 CRC. Of 362 autopsies, 34 (9.4%) had multiple CRC (26 in 2, 7 in 3, and 1 in 4). In the surgical cases, there was a similar rate of men and women with single and multiple CRC in the three age groups; more men than women in the 65-74 age group,