白血病患者因恐惧口内出血而限制使用牙刷。常用洗口或用棉花擦拭代替刷牙。这样常使牙龈炎、龋齿、口内炎症加重,口腔环境恶化。便成为口内出血和全身感染的病因。Lynch(1967)报告,75%白血病患者有口腔并发症。Peterson报告急性非淋巴性白血病发烧原因,32%来自于口内感染。Glickman(1972)报告牙垢等局和刺激引 Leukemia patients are limited to using toothbrushes for fear of bleeding in the mouth. Commonly used mouthwash or cotton swab instead of brushing. This often causes gingivitis, dental caries, increased inflammation in the mouth, the oral environment worsened. It has become the cause of oral bleeding and systemic infection. Lynch (1967) reported oral complications in 75% of leukemia patients. Peterson reports the cause of fever in acute non-lymphoid leukemia, 32% from oral infections. Glickman (1972) reports on plaque and other stimuli