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病史 患者,男,58岁,住院号263751。因发热,肝区痛于1979年5月22日入院。临床诊断为肝脓肿(阿米巴性肝脓肿合并细菌感染)。自5月23日起用灭滴灵治疗,每日四次,每次0.6克。6月16日觉手发麻、下肢痛、站立不稳、上下肢肌肉震颤。当时认为是链霉素毒性反应。灭滴灵用至26天后因病情好转而停药,上述症状也随之消失。后因病情复发于7月24日又用灭滴灵,每日四次,每次0.6克,用至19天时,又出现走路不稳、神志恍惚、四肢肌张力增高、肌纤维及肌束震颤、右手小幅度震颤、双下肢肌腱反射活跃、双上肢腱反射及跟腱反射不能引出,腹壁及提睾反射消失。脑脊液检查正常。如此迅速而广泛的神经系统损害考虑
Patient history, male, 58 years old, hospitalization number 263751. Due to fever, liver pain area on May 22, 1979 admission. Clinical diagnosis of liver abscess (amebic liver abscess with bacterial infection). Since May 23 with metronidazole treatment, four times a day, each 0.6 grams. June 16 feel numb, lower limb pain, standing instability, upper and lower limb muscle tremor. Was considered to be streptomycin toxic reaction. Metronidazole to 26 days after withdrawal due to improved condition, the above symptoms also disappear. After the recurrence of the disease on July 24 and metrobrel again, four times a day, each 0.6 grams, with 19 days, when walking again, trance, increased limb muscle tension, muscle fibers and fascia, Right hand minor tremor, tendon reflexes of both legs, upper extremity tendon reflexes and Achilles tendon reflex can not lead to abdominal and cremasteric reflex disappeared. Cerebrospinal fluid examination was normal. So rapid and extensive consideration of nervous system damage