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环核苷酸的生物化学环核苷酸系指3′,5′一环磷酸腺苷(cAMP)和3′,5′一环磷酸乌苷(cGMP),由于它们对神经冲动、激素等生理功能起着重要的介导作用,又被称为“第二信使”。cAMP 在1957年发现。cAMP 能激活细胞酶和使细胞膜的通透性发生改变。体内产生 cAMP 的主要场所是小肠上皮细胞,其次为大肠、肺、肾和肝细胞。其生成过程如下:
Cyclic Nucleotide Biochemistry Cyclic nucleotides refer to 3 ’, 5’ cAMP and 3 ’, 5’ cGMP, which, due to their impulsive effects on nerves, hormones and other physiology Function plays an important mediating role, also known as “second messenger.” cAMP found in 1957. cAMP activates cellular enzymes and alters cell membrane permeability. The main site of cAMP production in the body is small intestine epithelial cells, followed by large intestine, lung, kidney and liver cells. The generation process is as follows: